Celiac Disease Screen

Source

Blood

Mnemonic

CELIAC or TTG

Specimen Requirements

1 x 5 mL gold top SST tube (with labelled aliquot tube)

Minimum Blood Volume for Patients less than 45 kg (100 lb) Including Neonates and Pediatrics

Specimen Handling

Additional Information

Test screen for gluten intolerance (Celiac Disease)

Initial test of Celiac Disease Screen includes TTG and IgA. Additional reflexive assays will be ordered as required and may include Anti-Endomysial Antibodies and TTG IgG.

Testing Location

Serology

Testing Frequency

Monday - Friday

Alternate Name(s)

TTG IgA, Anti-endomysial antibodies, EMA and TTG IgG

Reference Interval

Anti-Endomysial Antibodies - negative
Tissue Transglutaminase Antibody IgA - < 20 kU/L
Tissue Transglutaminase Antibody IgG - Interpretative ranges:

< 1.0 - negative

1.0 to 2.0 - weak positive

> or = 2.0 - positive

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