| Source |
Blood |
| Mnemonic |
DZPM |
| Specimen Requirements |
2 x 5 mL red top tube, NOT SST
2.0 mL serum
Minimum Blood Volume for Patients less than 45 kg (100 lb) Including Neonates and Pediatrics |
| Specimen Handling |
RECORD the following on requisition:
· time of last dose
· dosage regimen (amount & frequency)
· how long patient has been on drug at present dosage
· date and time of collection |
| Additional Information |
Includes analysis of its metabolite Nordiazepam.
For additional information, see Half-life and time to Steady State.
The correlation between dose and plasma concentraton is influenced by pharmacogenetics.
|
| Testing Location |
Toxicology |
|
| Testing Frequency |
Monthly |
| Alternate Name(s) |
Valium |
| Reference Interval |
Therapeutic ranges indicate trough levels in serum under steady state conditions.
Diazepam + Nordiazepam = 0.7 to 7.4 µmol/L
Toxic levels: Diazepam + Nordiazepam = >10.5 µmol/L
|
