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Propafenone

Source Blood 
Mnemonic PPF 
Specimen Requirements

2 x 5 mL red top tubes, NOT SST

2.0 mL serum

Minimum Blood Volumes for Patients less than 45 kg (100 lb) Including Neonates and Pediatrics


Patient should be on drug at least 3 days prior to collection. Collect prior to morning dose.

 
Specimen Handling

 RECORD the following on requisition:

  • time of last dose
  • dosage regimen (amount & frequency)
  • how long patient has been on drug at present dosage
  • date and time of collection 
 
Additional Information For additional information, see Half-life and time to Steady State.

The correlation between dose and plama concentration is influenced by pharmacogenetics. 
Testing Location Toxicology 
Testing Frequency Monthly 
Alternate Name(s) Rythmol 
Reference Interval Therapeutic ranges indicate trough levels in serum under steady state conditions.

Therapeutic: 1.5 to 5.9 µmol/L

Toxic: not well defined 


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