Thiopental

Source	Blood
Mnemonic	THIOP
Specimen Requirements	2 x 5 mL red top tubes, NOT SST 2.0 mL serum Minimum Blood Volume for Patients less than 45 kg (100 lb) Including Neonates and Pediatrics
Specimen Handling	Remove serum to properly labelled aliquot tube for transport and storage. If Toxicology staff not on site, deliver specimen to DSC Accession.
Additional Information	Includes analysis of the metabolite Pentobarbital. For additional information, see Half-life and time to Steady State.
Testing Location	Toxicology
Testing Frequency	As required
Alternate Name(s)	Pentothal
Reference Interval	Hypnotic (sedation): 4 - 20.7 µmol/L Therapeutic coma: 124 - 413 µmol/L Anaesthesia: 20 - 536 µmol/L (Administered as intravenous, ultrashort-acting agent) Concentration at which toxicity occurs varies and should be interpreted in light of clinical situation.

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