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Molecular Pathology

Molecular Pathology Tests:

Lymphocyte Receptor Gene Rearrangement/Translocation

  • Immunoglobulin Heavy Chain
  • T-Cell Receptor
  • Bcl-1 t(11; 14)
  • Bcl-2 t(14; 18)
  • IgH Somatic Hypermutational Status

Viral and Bacterial Pathogen Detection

  • Cytomegalovirus
  • Herpes Simplex Virus (HSV 1 & 2)
  • Varicella Zoster Virus
  • Epstein-Barr Virus
  • Parvovirus B19
  • Mycobacterium spp (MTB Complex)
  • Human Polyomavirus (BK and JC)
  • Human Papillomavirus (Low risk subtypes 6 and 11: High risk subtypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67, 68 and 73)

Mutation Analysis

  • EGFR, BRAF, KRAS and PIK3CA (Lung Panel)
  • T790M EGFR (blood only)
  • KRAS, NRAS, BRAF, EGFR and PIK3CA (Colon Panel)
  • BRAF, NRAS, KRAS, HRAS, KIT, GNA11, GNAQ, PTEN, RAC, RPS27 and TERT (Melanoma/Thyroid Panel)
  • IDH1, IDH2, H3.3, TERT and TP53 (CNS/Neuro Panel)
  • CTNNB1, GNAS, KIT, PDGFRA, IDH1 and IDH2 (Sarcoma Panel)

Translocation Analysis

  • ALK, ROS and RET (Lung Fusion Panel, only for confirmation of IHC)

Microsatellite Analysis

  • Microsatellite Instability
  • 1p/19q Loss of Heterozygosity (Oligodendroglioma)

Epigenetics (Methylation)

  • MGMT Promoter Methylation

Human DNA Identity Testing

  • Identity/Contamination Test