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Alpha-1 Antitrypsin Phenotyping (Pi typing)

Source Blood
 
Mnemonic AATPI
Specimen Requirements 2 x 3.5 mL gold top SST tubes, includes 1 SST for AAT and 1 SST for Phenotyping.
Specimen Handling Send a copy of the requisition with specimens.

SST tube for AAT: Centrifuge and transport to DSC; DSC Accession deliver to Chemistry.

SST tube for Phenotyping:
PSC & RRL: Centrifuge and pour off, then transport serum to DSC.
Extra-regional: Centrifuge and pour off, and freeze serum before transporting to DSC.
DSC: Freeze serum upon receipt in lab; ensure frozen specimens do not thaw.
Additional Information Screen with AAT will be performed prior to referral on all samples except familial studies. If the AAT test results are greater than or equal to 0.9 g/L, Phenotyping test will be cancelled. If request is specifically for “familial studies”, contact Chemistry at 403-770-3265 to ensure test is not cancelled, but referred.
Testing Location DynaLife Dx
Testing Frequency
Alternate Name(s) Alpha-1 Antitrypsin Genotyping, Antitrypsin Familial Studies, Antitrypsin Pi, Pi Phenotyping, Protease Inhibitor
Reference Interval