Employee Login  |   Subscribe  |   Careers  |   Appointments
List All Test Names Beginning With:
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Alpha-Galactosidase

Referred out for testing

Source Blood
Mnemonic BGLBL

BGL Test Name field: a-Galactosidase
Specimen Requirements 1 x 4 mL dark green top sodium heparin tube or 1 x 4 mL dark green lithium heparin tube, NOT PST.

Serum will not be accepted.

Minimum: 0.25 mL plasma
Specimen Handling Send a copy of the requisition with the specimen.

PSC:
Centrifuge, transfer plasma to aliquot tube, write "NaHep" or "LiHep" on the aliquot tube, and transport on ice to DSC.

RRL:
Centrifuge, transfer plasma to aliquot tube, write "NaHep" or "LiHep" on the aliquot tube, and transport on ice to ACH.

Extra-regional:
Centrifuge, transfer plasma to aliquot tube, write "NaHep" or "LiHep" on the aliquot tube, and freeze prior to transport to DSC.

DSC:
Freeze plasma upon receipt in lab; ensure frozen specimens do not thaw.
Additional Information

This test is for the investigation of Fabry disease in male patients based on clinical presentation.

The measurement of plasma alpha-galactosidase A activity is not a recommended diagnostic test for Fabry disease in females. In addition to a reported 30% of affected female patients showing normal enzyme activity, the Biochemical Genetics laboratory has identified several female patients with moderately decreased enzyme activity that were not subsequently found to have a detectable GLA mutation. Recommend referral to the ACH Inherited Metabolic Disorders Clinic for detailed investigation and/or application for out-of-province funding for GLA gene-based testing.

Testing Location ACH Biochemical Genetics Lab
Testing Frequency Twice monthly
Alternate Name(s) GLA
Reference Interval Provided on test report.