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C-1 Esterase Inhibitor, Total Protein and Function

Source Blood
Mnemonic C1ESTER and C1F
Specimen Requirements

Collections performed at acute care (RRL) sites and all PSCs.
Test cannot be collected by Mobile Collection Service (MCS).

1 x 3.5 mL gold top SST tube
2.0 mL serum

Keep tubes cold (immerse in ice water or crushed ice) prior to and immediately after collection. 

Specimen Handling

PSC:
Allow to clot on ice, centrifuge at 4ºC + 2ºC, separate into 2 x 1 mL aliquots, and transport on ice to DSC.

RRL and extra-regional: 
Allow to clot on ice, centrifuge at 4ºC + 2ºC, separate into 2 x 1 mL aliquots, and freeze immediately, then transport to DSC.

DSC:
Freeze specimens upon receipt in lab; ensure frozen specimens do not thaw.

Additional Information Total protein and functional protein levels will be determined.
Testing Location University of Alberta
Testing Frequency
Alternate Name(s) Immuno-Complement Test, C-1 Inactivator
Reference Interval