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Creutzfeld-Jakob Disease - CSF

Referred out to Alberta Provincial Laboratory for Public Health (ProvLab)


Source CSF
Mnemonic CJD 14-3-3
Specimen Requirements See CSF Collection Guidelines

Use sterile screw caped tubes

2-3 mL CSF
Specimen Handling

Warning to Ordering Physician:
In cases of suspected CJD, contact the microbiologist on call at 403-770-3757 before collecting or sending any specimens.

CLS staff:
CONTACT MICROBIOLOGIST ON CALL IMMEDIATELY at 403-770-3757 and refer to CLS BCERP Manual if there is no "C" Lab Level III/IV Alert Code already appended in PathNet.

Specimen may also be received with requisition stating "CJD", "Creutzfeldt-Jakob Disease", "Quaking Induced Conversion", "Tau Protein",  "Protein 14-3-3", "Gerstmann-Straussler-Scheinker disease", "Fatal Familial insomnia" (or with requests to rule out any of the above),

Transport by TDG Provincial Laboratory. Provincial Laboratory will forward to Health Canada for testing.

Additional Information Send specimen in a separate bag with a photocopy of the requisition.

Testing Location
Testing Frequency
Alternate Name(s) CJD, Familial Creutzfeld-Jakob Disease, Fatal Familial Insomnia, Gerstmann-Straussler-Scheinker Disease, Protein 14-3-3, Sporadic Creutzfeld-Jakob Disease, Variant Creutzfeld-Jakob Disease
Reference Interval