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JAK2 Mutational Analysis

Source Blood, bone marrow
Mnemonic

JAK2 PB (Blood)

JAK2 BM (Bone Marrow)

Specimen Requirements Whole blood: 1 x 4 mL lavender top EDTA tube

Do not collect in same tube with any other test. Specimens poured off from other EDTA tubes (e.g. CBC) are NOT ACCEPTABLE
.


Bone marrow:
 1 x 4 mL lavender top EDTA tube with minimum of 0.5 mL of bone marrow in each tube
Specimen Handling Send all specimens at room temperature directly to DSC Molecular Hematology in a separate bag with a copy of requisition (exception: tests ordered in SCM do not require a requisition).


DSC Accession: after 16:30, store at 4ºC.
Additional Information Molecular investigations must be DEDICATED specimens to avoid sample contamination.

Peripheral blood specimens must be accompanied by a completed CLS Molecular Hematology requisition (REQ9053MH).

Bone marrow specimens must be accompanied by a completed Bone Marrow Pathology requisition (REQ9061BM).
Testing Location Molecular Hematology
Testing Frequency Every 3 to 4 weeks.
Alternate Name(s) JAK2- V617F; Janus Kinase 2 Mutation
Reference Interval Negative (normal)