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Pipecolic Acid - Blood

Referred out for testing

Source Blood
Mnemonic

BGLBL

BGL Test Name field: Pipecolic

Specimen Requirements

1 x 4 mL dark green top sodium heparin tube. 1 x 4 mL dark green lithium heparin, NOT PST, is also acceptable.

Serum will not be accepted.

Minimum: 0.25 mL plasma

Requires a four-hour fast, or just prior to next feed for newborns.

Specimen Handling

Send a copy of the requisition with the specimen.

PSC:
Centrifuge, transfer plasma to aliquot tube, write "NaHep" or "LiHep" on the aliquot tube, and transport on ice to DSC.

RRL:
Centrifuge, transfer plasma to aliquot tube, write "NaHep" or "LiHep" on the aliquot tube, and transport on ice to ACH.

Extra-regional:
Centrifuge, transfer plasma to aliquot tube, write "NaHep" or "LiHep" on the aliquot tube, and freeze prior to transport to DSC.

DSC:
Freeze plasma upon receipt in lab; ensure frozen specimens do not thaw.

Additional Information For the investigation of peroxisomal biogenesis disorders, this test should be ordered in conjunction with Fatty Acids, Very Long Chain (with Phytanic and Pristanic). For the investigation of pyridoxine-dependent seizures, the sensitivity of this test is known to be reduced by the length of time the patient is receiving pyridoxine prior to sample collection.
Testing Location ACH Biochemical Genetics Lab
Testing Frequency Monthly; must notify ACH Biochemical Genetics Lab for priority turn-around.
Alternate Name(s)
Reference Interval Provided on test report.