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Prostate Specific Antigen, Fractionated/Free

Source Blood
Mnemonic FPSA
Specimen Requirements

1 x 3 mL or 4.5 mL light green (mint) top PST tube.  Gold top SST tube also acceptable.

Minimum 1 mL plasma or serum

Minimum Whole Blood Volumes for Microcollections

Specimen Handling
Additional Information

Recommend waiting 2 weeks after DRE to collect blood for PSA.

Test includes Total PSA, Free PSA, and the Total/Free PSA ratio.

Testing Location Chemistry-DSC
Testing Frequency Daily
Alternate Name(s) Free PSA; PSA, Fractionated/Free
Reference Interval

In patients with Total PSA concentrations of 4 - 10 ug/L, the possibility of finding Prostate Cancer on needle biopsy by age in years is:

  % Free PSA 

  50-59 Years  

  60-69 Years 

  70-150 Years  

< 11   %

49 %

58 %

65 %

11-18 %

27 %

34 %

41 %

19-25 %

18 %

24 %

30 %

> 25   %

 9 %

12 %

16 %