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Prostate Specific Antigen, Total

Source Blood
Mnemonic PSA
Specimen Requirements

1 x 3 mL or 4.5 mL light green (mint) top PST tube.  Gold top SST tube also acceptable.

0.5 mL plasma or serum.

Minimum Whole Blood Volumes for Microcollections

Recommend waiting two weeks after DRE to collect blood for PSA.

Specimen Handling
Additional Information

History form is not required.

As per the 2014 Canadian Task Force on Preventive Health Care recommendations, the PSA test should not be used for prostate cancer screening of healthy, asymptomatic men. (Bell et al. 2014. CMAJ.186 (16) 1225-1234.)

Testing Location Chemistry-DSC
Testing Frequency Daily
Alternate Name(s) PSA, Total
Reference Interval Male:

1 day – 49 years

0.0-2.5 mg/L

50 – 59 years

0.0-3.5 mg/L

60 – 69 years

0.0-4.5 mg/L

70 – 150 years

0.0-6.5 mg/L