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Theophylline

Source Blood
Mnemonic THEO
Specimen Requirements

1 x 3 mL light green (mint) top PST tube.  Gold top SST tube also acceptable.

Minimum Whole Blood Volumes for Micro-Collections using Microtainers

Collect specimen 0-60 minutes prior to next oral dose.

For IV dosing, collect 30 minutes after completion of loading dose and 4-6 hours after beginning infusion.

Specimen Handling
Additional Information

Record time of last dose on requisition.

For additional information, see Half-life and Time to Steady State.

Testing Location Chemistry-FMC
Testing Frequency Daily
Alternate Name(s) Somophyllin, Aminophylline
Reference Interval

Therapeutic range:

0-31 days

25.0-110-0 mmol/L

32 days – 150 years

55.0-110.0 mmol/L

Theophylline Stimulation Range 0 - 1 year: 33.0 - 55.0 mmol/L

Click here for critical values.