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Thiocyanate

Source Blood
Mnemonic THIO
Specimen Requirements

2 x 3.5 mL gold top SST tubes preferred; 2 x 3 mL light green (mint) top PST tubes are also acceptable. 

2.0 mL serum (or plasma)

Minimum Whole Blood Volumes for Micro-Collections using Microtainers

Specimen Handling DO NOT store serum (or plasma) on gel tube.  Remove to properly labelled aliquot tube for transport and storage.
Additional Information

This test is indicated for measuring thiocyanate toxicity in patients on long-term nitroprusside therapy and with hepatic or renal dysfunction. It is not intended for monitoring occupational health surveillance due to cyanide exposure.

Stat requests have restricted clinical indications and require review and approval by CLS Medical & Scientific Staff. Contact LIC at 403-770-3600 for Pathologist On Call information.

Testing Location Analytical Toxicology
Testing Frequency As required
Alternate Name(s) Sodium Nitroprusside, Nipride
Reference Interval Thiocyanate levels up to 0.5 mmol/L are seen with nitroprusside therapy.
Thiocyanate levels greater than 1.4 mmol/L are reportedly toxic.