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Thrombophilia Screen

Source Blood
 
 
Mnemonic THROMB 
 
 
Specimen Requirements

Test cannot be collected by Mobile Collection Service (MCS).

Adult:
4 x 4.5 mL blue top sodium citrate tubes
AND 1 x 4 mL lavender top EDTA tube

Pediatric:
3 x 2.7 mL short-draw blue top sodium citrate tubes AND 1 x 3 mL short-draw lavender top EDTA tube.

Specimens MUST be accompanied with a copy of the original requisition and Thrombophilia Screen/Related Procedures history form. Phone Special Coagulation 403-770-3599 or 403-770-3598 with any questions (exception: electronic orders submitted through Sunrise Clinical Manager - SCM).

When using a winged blood collection set (butterfly needle) a discard tube must be used to remove the air in the tubing, if the citrate tube is the first tube drawn.

Specimen Handling PSC and RRL:
Send specimens UNSPUN at room temperature directly to DSC Special Coagulation. Must arrive within 2 hours of collection.

Extra-regional:
Lavender tube - ship unspun at room temperature.
Blue top tubes - centrifuge at 3500 rpm for 20 minutes, aliquot plasma into 8-10 plastic tubes. Freeze and transport frozen to DSC Special Coagulation.

Note: Weekend collections are not recommended.

 
Additional Information Testing includes antithrombin, protein C, protein S, activated protein C resistance, factor V leiden, factor II variant, lupus type inhibitor (THROMB order includes Thrombophilia Screen and DNATR).
 
 
Testing Location Special Coagulation
Testing Frequency
Alternate Name(s) Hypercoagulable screen/workup; Thrombosis study/workup

 
Reference Interval