Blood Component Administration

The administration of blood products is guided by the related procedures in the Regional
Nursing Policy and Procedure Manual. This includes information on administration sets,
needle size and infusion rates. Policy B-3 Blood Component/ Product Administration includes
information about the following:

  • Pretransfusion testing
  • Transfusion identification bands
  • Issuing of blood components/ products
  • Administration of blood components/ products
  • Performing checks prior to transfusion
  • Transfusion reactions

Intravenous Immune Globulin (IVIG) Administration Information

The following guidelines are for the infusion of IVIG preparations. These guidelines have
been prepared from the information provided by the manufacturer in the product insert.

  • Most IVIG preparations are in a 10% concentration.
  • The compatible solution for all 10% IVIG preparations is D5W
    (5% dextrose in water).

Commercial Product
Name (Concentration)

Product Name on Transfusion Tag

Product Insert Reference

Initial
Infusion
Rate

Maximum Infusion Rate

Comments

Manufacturer
Privigen 10%

PRIVIGEN IVIG 10%

30 May 2008

0.3 mL/ kg/
hour

7.2 mL/ kg/ hour

Compatible with D5W

 
CSL Behring
Gamunex/ IVIGnex 10%

GAMUNEX

08841856 (Rev July 2003)

0.01 to 0.02 mL/ kg body weight/ per minute for 30 minutes

 0.14 mL/ kg body weight/
minute

Only product suitable for rapid infusion rates.

Suitable for diabetics.
Talecris Biotherapeutics
Gammagard S/D 10%

GAMMAGARD

Revised July 2000

0.5 mL/ kg/ hour

(0.008 mL/ kg body weight/ per minute for 30 minutes)

8 mL/ kg/ hour

(0.133 mL/ kg body weight/ per minute)

 Antecubital veins are recommended site for
infusion. Recommended for IgA deficiency with anti-IgA.
Baxter Corporation
Gammagard Liquid 10%

LIQ GAMMAGARD

April 12, 2006

0.5 mL/ kg/ hour

(0.008 mL/ kg body weight/ per minute for 30 minutes)

8 mL/ kg/ hour

(0.133 mL/ kg body weight/ minute)

 Antecubital veins are recommended site for infusion.
Baxter Corporation
CytoGam Cytomegalovirus Immune Globulin Intravenous (Human)

CMV IVIG

4-25-2000

15 mg IG/ kg/ hour

60 mg IG/ kg/ hour

 Do not exceed 75 mL/ hour
CSL Behring

  • If infusion at the initial rate is well tolerated, gradually increase the rate of infusion.
  • If side effects occur, the rate may be reduced.
  • The infusion may be interrupted until symptoms subside and the infusion restarted
    at the rate that is comfortable for the patient.

Formula for calculating the rate per hour: 
Infusion rate (mL) x body weight (kg) x 60 minutes (hr) = rate (mL) per hour

Examples for a 70 kg patient: 
Gammunex: 0.01 mL x 70 kg x 60 minutes = 42 mL/hour
Gammagard: 0.5 mL x 70 kg x 1 hour = 35 mL/ hour