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Molecular Hematology

The Molecular Hematology division performs:

  • Advanced biochemical (protein) and molecular (gene) analysis for disorders of hemostasis and thrombosis including: carrier detection for hemophilia A and B, von Willebrand disease subtyping by VWF multimer analysis, and inherited risk factors for thrombosis (factor V Leiden and factor II polymorphism analysis)
  • Molecular analysis by RT-PCR (qualitative) and real-time PCR (quantitative) for diagnosis and monitoring of patients with hematologic malignancies including: CML, ALL and APL
  • Molecular analysis of hematopoietic cell chimerism by short tandem repeat (STR) after bone marrow/stem cell transplantation       
  • Mutation detection in genes linked to prognosis of patients with normal karyotype AML (FLT3, NPM1, and CEBPA)
  • Molecular detection of JAK2 V617F mutation related to myeloproliferative neoplasms
  • GAP PCR for detection of HBA1, HBA2 deletional variants in alpha thalassemia

For questions related to the services provided by Molecular Hematology, call 403-770-3699.

Service Hours

Regular hours of operation (exclusive of statutory holidays): 0730-1630h Monday to Friday

Completing the Test Request Form

See Molecular Hematology Requisition

Specimen Labeling Criteria

All specimens must be labeled with the following information fixed to the specimen container:

  • Patient's last name and given name
  • Date of birth
  • Hospital or provincial health care number
  • Date and time of collection

If specimens are not labeled or are mislabeled, a recollection may be necessary, resulting in a delay in processing.

Collection Guidelines

For specimen requirements and handling instructions refer to individual tests in the above alphabetical list.