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Thrombophilia Screen

Source

Blood

 
Mnemonic

THROMB 
and
DNATR

 
Specimen Requirements

Adult: 4 x 5 mL blue top sodium citrate tubes (4.5 mL draw)
AND 1 x 5 mL lavender top EDTA tube

Pediatric: 3 x short-draw (2.7 mL draw) blue top sodium citrate tubes AND 1 x short-draw lavender top EDTA tube.

Specimens MUST be accompanied with a copy of the original requisition and Thrombophilia Screen/Related Procedures history form. Phone Special Coagulation 770-3599/770-3598 with any questions.

When using a winged blood collection set (butterfly needle) a discard tube must be used to remove the air in the tubing, if the citrate tube is the first tube drawn.

 
Specimen Handling

PSC and RRL: Send specimens UNSPUN at room temperature directly to DSC Special Coagulation. Must arrive within 2 hours of collection.

Extra-regional
: Lavender tube - ship unspun at room temperature.
Blue top tubes – centrifuge at 3500 rpm for 20 minutes, aliquot plasma into 8-10 plastic tubes. Freeze and transport frozen to DSC Special Coagulation.

Note: Weekend collections are not recommended.

 
Additional Information Testing includes antithrombin , protein C, protein S, activated protein C resistance, factor V leiden, factor II variant lupus type inhibitor. 
Testing Location Special Coagulation 
Testing Frequency  
Alternate Name(s) Hypercoaguable screen/workup, Thrombosis study/workup 
Reference Interval  


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