Employee Login  |   Subscribe  |   Careers  |   Appointments
List All Test Names Beginning With:
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Celiac Disease Screen

Source Blood
Mnemonic CELIAC or TTG
Specimen Requirements

1 x 3.5 mL gold top SST tube

PSC only: 1 x 5 mL orange top RST tube is acceptable within one hour of lab closing.

Minimum Whole Blood Volumes for Microcollections

Specimen Handling
Additional Information

Test screen for gluten intolerance (Celiac Disease)

Initial test of Celiac Disease Screen includes TTG IgA. The current method has the ability to determine whether a sample has low IgA levels. Additional reflexive assays will be ordered as required and may include Anti-Endomysial Antibodies and TTG IgG.

Physician Information:
Initiating a gluten-free diet prior to referral or prior to screening will interfere with the diagnostic tests for celiac disease.  Please note that individuals may exhibit a wide range of responses to gluten challenge over varying periods of time.  Some patients only require a diet containing gluten (minimum of 3 g/day gluten or approximately 1-2 slices of bread/day) for at least 2 weeks to exhibit histological changes and at least 4 weeks for tTG IgA levels to increase.  Others may require a challenge for as long as two years prior to the development of intestinal injury or antibody response. Celiac disease serology during the challenge should be repeated every 4-6 months or immediately with the development of symptoms.

Click here to view a diagnostic algorithm.

Testing Location Immunochemistry
Testing Frequency Weekdays
Alternate Name(s) Anti-endomysial antibodies, Celiac Marker, CSA, EMA, Tissue Transglutaminase Antibody IgA, TTG IgA.
Reference Interval

Anti-Endomysial Antibodies - negative
Tissue Transglutaminase Antibody IgA and IgG - < 15.0 kIU/L