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Erythrocyte Sedimentation Rate

Source Blood
Mnemonic ESR
Specimen Requirements

Lab collections at all sites except ACH and CRL:|
1 x 1.36 mL black top PLASTIC sodium citrate ESR tube, whole blood
Note: These tubes are used for ESR testing ONLY.
-
Allow tube to fill until vacuum is exhausted (blood will stop entering the tube).
- Tube must be filled to the minimum fill line and not more than the maximum fill line on the tube.
- Mix tube immediately, inverting 3 - 4 times.
- When using a winged collection set (butterfly needle), a discard tube must be used to remove the air in the tubing, if only a black top ESR tube is drawn or is the first tube drawn.

ACH, CRL and collections by non-laboratory staff ONLY:
1 x 4 mL or 1 x 3 mL lavender top EDTA tube OR 3 x MAP EDTA tubes filled to the 500 µL mark
- Mix well by inverting tube 8 - 10 times
- Minimum volume 1.5 mL whole blood

Specimen Handling DO NOT centrifuge.
Additional Information

ESRs are unreliable in anemia, leading to false increases. Cannot report ESR if RBCs are <2.5 x 1012/L.

In most cases, C-Reactive Protein (CRP) is the preferred test over ESR. If an ESR is ordered, CLS will perform a CRP for most patients and the ESR will be cancelled.
For more information, refer to:
    - CLS Memo C-Reactive Protein Substitution for Erythrocyte Sedimentation Rate (
http://www.calgarylabservices.com/files/HealthcareProfessionals/Memos/2017-10-17.pdf)
    - AHS Memo C – Reactive Protein (CRP) Substitution for Erythrocyte Sedimentation Rate (ESR) (
http://www.albertahealthservices.ca/assets/wf/lab/wf-lab-crp-substitution-for-esr.pdf)

Testing Location Hematology-All Sites
Testing Frequency Daily
Alternate Name(s) ESR, Sedimentation Rate
Reference Interval
 Children (0-12 years)  0-10 mm
 Female (>12 years)  0-20 mm
 Male (>12 years)  0-10 mm