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Hereditary Spherocytosis

Source Blood

 
Mnemonic

HS

Must also collect CBC, RET and DAT.

 

Specimen Requirements

Adult: 1 x 8.5 mL yellow top ACD-A tube AND 2 x 4 mL lavender top EDTA tubes

Pediatric: 1 x 1.8 mL blue top sodium citrate tube AND 2 x 3 mL short-draw lavender top EDTA tubes


 

Specimen Handling

Specimens submitted to CLS from within Alberta: Mix well. DO NOT centrifuge or freeze. Deliver immediately to Flow Cytometry. Extra-regional specimens must be accompanied by a stained peripheral blood smear (PBS) slide.

Specimens submitted to CLS from outside Alberta: DO NOT centrifuge or freeze samples. Ship at 4oC, using an overnight courier. All requests must be accompanied by a stained peripheral blood smear (PBS) slide. Please follow Flow Cytometry Shipping and Handling instructions when sending to CLS.

 

Additional Information

Test includes Complete Blood Count (CBC which includes DIFF), Reticulocyte Count (RET), and Direct Antiglobulin Test (DAT).

Please indicate RBC transfusion history on requisition. Do NOT test if RBC transfusion within 3 months.

Specimens submitted to CLS from outside Alberta: Use FC3200EP Flow Cytometry Out of Province Requisition.
For pricing and billing, refer to Flow Cytometry Billing and Pricing.

 

Testing Location Flow Cytometry
Testing Frequency Mondays
Alternate Name(s) Erythrocyte Fragility, Osmotic Fragility - Erythrocyte, Red Blood Cell Osmotic Fragility
Reference Interval Provided on report.