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MADL Scleroderma Profile

Source Blood
Mnemonic SCLERO
Specimen Requirements 1 x 3.5 mL gold top SST tube

1 mL serum
Specimen Handling Centrifuge and pour off serum.

Send serum specimen in a separate bag with a photocopy of the requisition.
Additional Information Testing for the following antibodies is included:
PM/Scl, Topisomerase I (Scl-70), CENP-B, Fibrillarin (U3 RNP or Scl34). 
Testing Location Mitogen Advanced Diagnostics Lab (Dr. Fritzler)
Testing Frequency
Alternate Name(s) CENP-B Antibodies; Fibrillarin Antibodies; Scl34 Antibodies; Scleroderma Profile, MADL; U3 RNP Antibodies
Reference Interval